Today I started receiving this error when trying to start IIS on my workstation:

The Process cannot access the file because it is being used by another process (Exception from HRESULT: 0x80070020)
I discovered that the error was occurring because I recently installed Skype and apparently it takes over port 80 and 443 on the machine it is installed on. To fix the problem, you need to uncheck the option in the advanced connection options.

Uncheck "Use port 80 and 443 as alternatives for incoming connections".
That fixed my problem.
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